Gli-Gar contains 300 mg of garlic extract. Garlic (Allium sativum) that, belongs to the Alliaceae family, is well known as spice, and is also used for certain ailments and physiological disorders. Garlic contains water-soluble sulphur compounds, especially allicin.
In ancient Egypt, the number of garlic distributed to the workers who built the pyramids was inscribed in hieroglyphs on the pyramid walls. It has been used to alleviate fatigue or to speed up recovery from physical fatigue and to enable workers to withstand heavy work. Likewise, in ancient Rome, garlic was given to soldiers and athletes as a tonic (stimulant). Recently, the anti-fatigue effect of garlic has been investigated by many researchers. The anti-fatigue effect of garlic is thought to be due to the increase in peripheral circulation (blood circulation in the muscles) and the inhibition of oxidative substances that occur as a result of lactic acid accumulation due to fatigue. Reducing oxidative damage also supports immunity and acts as a protector against infectious diseases. Waste materials in muscles as a result of sport competitions or intense performance are excreted into the blood and cause fatigue or muscle pain. Peripheral circulation accounts for 90% of the total blood vessels in the body. Peripheral circulation delivers the nutrients they need to cells and organs through the blood and removes metabolites and wastes that form in cells or organs. This helps the muscles to recover and regain their former strength as a result of intense performance, to maintain their physical strength, and to get rid of fatigue quickly. The fact that garlic lowers blood pressure by relaxing blood vessels in the peripheral circulation increases the fluidity of the blood, blood supply to the muscles, and as a result, physical strength and performance. It also allows the heart to pump more blood to the muscle tissues and pull more blood back from the muscles to the heart. This causes the muscles to produce more energy and the waste materials that are formed as a result of intense work and cause fatigue to be removed from the muscles faster. As a result, the muscles produce more power with more energy, and the waste materials are removed quickly, so they perform tirelessly for longer.
Moderate exercise is useful for preventing lifestyle-related diseases or increasing physical strength, but excessive exercise itself can be a form of stress. Increased free radical levels as a result of excessive exercise cause long-term fatigue and damage to the body. Under these extreme exercise conditions, the concentration of lipid peroxide in the liver or muscles increases. Lipid peroxide is an oxidative substance and causes damage to tissues. Garlic reduces the amount of lipid peroxide by activating enzymes that scavenge oxidative substances such as superoxide dismutase. This also leads to a decrease in the levels of other oxidative substances, such as hydroxyl radicals.
Physical or mental stress leads to a breakdown of the immune system. Disruption of immunity can cause damage to cells and tissues. In cases where immunity is impaired, the risk of contracting infective diseases increases. When infected, the body's response is to produce various inflammatory or cell damaging substances or cells in order to limit or destroy this infectious agent. Supporting the immune system prevents the formation of this tissue and cell damage.
Exercise or work reduces the reserves of glycogen, a source of energy in the liver or muscles, which leads to a lack of energy supply or oxygen to the muscles, thus causing muscle fatigue. It has been reported that the garlic, that is also contained in the formulation of Gli-Gar, has many nutritional components such as magnesium, iron, copper, zinc, sulphur compounds, amino acids, vitamins and carbohydrates. These components undoubtedly contribute to recovery from the period of fatigue. In addition, L-cysteine contained in Gli-Gar is an amino acid and is found in the structure of proteins. L-cysteine both promotes protein formation in the muscles and is responsible for the above-mentioned effects by forming sulphur compounds in the body.
The effects of garlic extract on humans have been widely studied. For example, consuming garlic oil extract for 6 weeks has been shown to improve performance and exercise tolerance in patients with coronary disease. In another study, it was stated that garlic extract improved fatigue symptoms as a result of exercise tests in athletes, increased the threshold of knee burning and pain, and in another study, it was stated that it increased oxygen intake during intense exercise. In addition, the application of garlic extract has been reported in many clinical studies to reduce systemic fatigue or unidentified complaints accompanying the common cold.
Glucosamine is a hexosamine sugar that is naturally produced in humans. Hyaluronic acid is an important precursor in the biosynthesis of many connective tissue macromolecules such as proteoglycans, glycosaminoglycans (GAGs), glycolipids, and glycoproteins. Chondroitin sulphate is a prominent GAG found in articular cartilage. Its hydrophilic properties allow the articular cartilage to absorb relatively large amounts of water, thereby transmitting and absorbing compressive forces on the cartilage.
One of the common musculoskeletal-tendon disorders encountered by athletes and sports players is tendinopathies. Tendinopathies are inflammatory and degenerative diseases that impair the quality and mechanics of the tendon. Some tendons are more affected by tendinopathies than others; In particular, the supraspinatus and biceps brachy tendons, the extensor and flexor tendons of the forearm, the patellar tendon, the Achilles and tibialis posterior tendons are the most commonly affected.
Several conservative strategies have been proposed to treat tendinopathies and prevent their recurrence. In the last few years, it has been recommended to use oral supplements to support the physiological cycle of tendon tissue in order to prevent inflammation and degeneration. These recommendations include substances found in the natural structure of joints and cartilage, such as glucosamine and chondroitin. Glucosamine and chondroitin sulphate increase collagen synthesis, improve mechanical properties, improve the organization of collagen bundles and resistance to fatigue, help in the treatment of pain. Thanks to the glucosamine and chondroitin it contains, Gli-Gar can also be useful in tendinopathies, one of the most common ailments encountered by athletes.
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